The article deals with an actual topic related to the research of problems in the field of historical and cultural heritage with the use of geoinformation technologies. In connection with the growing interest on the part of professional communities and tourist traffics to museum institutions, their history, the legacy that they preserve, it becomes necessary to present information about it in a compact format, reflecting the main content, and provide free access to such resource. The research is interdisciplinary in nature due to methods and technologies, first of all geoinformation systems (GIS) which bring significant prospects in the research of the humanitarian sphere. Foreign experience of applying GIS in studying the museum heritage demonstrates the high interest of the scientific community to this problem. Many projects are carried out at a high professional level with cooperation of museum staff, historians and specialists in the field of information technology. This allowed us to obtain a quality product that is convenient for use. In Russia there is an experience of learning the historical and cultural heritage with the use of GIS, but the development of museum GIS is isolated. Permanent transformation of the museum network in Russia and in regions requires the collection of complex information and its systematization for the subsequent presentation as a possible basis for studying the museums themselves, the historical and cultural heritage that they save, for the exchange of experience of museum employees, and for tourists. Creation of GIS “Museum network of the Altai Territory” provides such opportunities. Its development is carried out on the basis of a wide range of sources, with including on the database, with including museums of educational institutions, departmental museums, information about which is difficult to obtain. GIS will allow to recreate the chronology of the creation of museums by using the visualization methods, the formation of their profile groups, to assess the source material potential of museum collections at the level of expositions, and to develop tourist routes.